000			03155cam a2200433Mu 4500
001			ocn877771869
003			OCoLC
005			20230110113547.0
006			m d
007			cr cnu---unuuu
008			140419s2014 xx o 000 0 eng d
020			_a9780128008324 (electronic bk.)
020			_a0128008326 (electronic bk.)
035			_a(OCoLC)877771869
035			_a760687
040			_aEBLCP _beng _cEBLCP _dN$T
049			_aN$TA
050		4	_aQD415
072		7	_aSCI _x013040 _2bisacsh
082	0	4	_a547 _223
100	1		_aRice, Joseph E.
245	1	0	_aOrganic Chemistry Concepts and Applications for Medicinal Chemistry _h[electronic resource].
260			_aBurlington : _bElsevier Science, _c2014.
300			_a1 online resource (219 p.)
500			_aDescription based upon print version of record.
505	0		_aFront Cover; Organic Chemistry Concepts and Applications for Medicinal Chemistry; Copyright; DEDICATION; CONTENTS; PREFACE; Chapter 1 -- Bonding in Organic Compounds; ATOMIC ORBITALS; HYBRID ORBITALS; RESONANCE; AROMATICITY; REFERENCE; Chapter 2 -- The Three-Dimensional Structure of Organic Compounds; ISOMERS; STEREOISOMERISM AT SATURATED CENTERS; PROCHIRALITY; STEREOISOMERISM AT UNSATURATED CENTERS; CONFORMATIONS; REFERENCE; Chapter 3 -- Functional Groups; COMMON FUNCTIONAL GROUPS; THE ELECTRONIC EFFECTS OF FUNCTIONAL GROUPS; REFERENCES; CHAPTER 4 -- ACIDS AND BASES*; IONIZATION
505	8		_aESTIMATING ACID/BASE STRENGTHLEWIS ACIDS AND BASES; Chapter 5 -- Partition Coefficients; WHAT IS A PARTITION COEFFICIENT?; EFFECT OF STRUCTURE ON PARTITION COEFFICIENTS; REFERENCE; Chapter 6 -- The Nomenclature of Cyclic and Polycyclic Compounds; COMMON HETEROCYCLES; FUSED-RING SYSTEMS; SUBSTITUENTS AND SATURATION; BRIDGED RINGS; SPIRO RINGS; SPECIAL CLASSES OF COMPOUNDS; Chapter 7 -- Drug Metabolism; PHASE I: OXIDATIVE PROCESSES; PHASE I: REDUCTIONS; PHASE I: HYDROLYSIS; PHASE II: CONJUGATION; MISCELLANEOUS PHASE II PROCESSES; REFERENCES; INDEX
520			_aOrganic Chemistry Concepts and Applications for Medicinal Chemistry provides a valuable refresher for understanding the relationship between chemical bonding and those molecular properties that help to determine medicinal activity. This book explores the basic aspects of structural organic chemistry without going into the various classes of reactions. Two medicinal chemistry concepts are also introduced: partition coefficients and the nomenclature of cyclic and polycyclic ring systems that comprise a large number of drug molecules. Given the systematic name of a drug, the reader is g.
650		0	_aClinical chemistry.
650		0	_aBiochemistry.
650		0	_aOrganic compounds.
650		7	_aSCIENCE / Chemistry / Organic _2bisacsh
655		4	_aElectronic books.
776	0	8	_iPrint version: _aRice, Joseph E. _tOrganic Chemistry Concepts and Applications for Medicinal Chemistry _dBurlington : Elsevier Science,c2014 _z9780128007396
850			_aKCNL
856	4	0	_3EBSCOhost _uhttps://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=760687
910			_acpp1723AUTO
942			_cEBK
999			_c35478 _d35478